报告人：孔道春

时间：2018年5月24日，14:00-16:00

地点：理科楼430会议室

报告摘要： The DNA origins in the fission yeast and metazoans are five to ten times larger than that in the budding yeast. This indicates that the mechanism of DNA replication initiation is different among eukaryotes. After replication initiation, replication forks traverse across chromatin and will encounter an extensive array of replication barriers. Replication forks stalling at those barriers tend to collapse. Fortunately, eukaryotic cells have developed sophisticated mechanisms to prevent stalling forks from collapse. In my talk, I will present a few crucial cellular mechanisms that are recently uncovered in relation to replication initiation, fork stability and maintenance of genomic integrity.

孔道春教授简介：

博士生导师。北京大学生命科学院、北大-清华生命科学联合中心、蛋白质工程与植物基因工程国家重点实验室教授，973项目首席科学家。现任全国酵母协会会长。亚洲冷泉港：“DNA metabolism, genomic stability and human disease”国际会议组织者。《DNA Repair》, Editor。

研究兴趣： Chromosomal DNA replication, replication fork stability, recombination and DNA break repair.